{
  "meta": {
    "data_length": 1,
    "message": "Biomarker id bmkr:21 retrieved successfully",
    "request_url": "http://api.moalmanac.org/biomarkers?biomarker_id=bmkr%3A21",
    "status": "success",
    "status_code": 200,
    "timestamp_elapsed": 0.001649,
    "timestamp_received": "2026-09-25T01:16:30.942777+00:00Z",
    "timestamp_returned": "2026-09-25T01:16:30.944426+00:00Z",
    "trace_id": "eb2c2bfe-14b5-4e34-9c05-28092f884071"
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    "name": "Molecular Oncology Almanac",
    "license": "GPL-2.0",
    "release": "draft",
    "url": "https://dev.moalmanac.org",
    "last_updated": "2026-08-02"
  },
  "data": [
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      "id": "bmkr:21",
      "type": "CategoricalVariant",
      "name": "ERBB2 amplification",
      "constraints": [
        {
          "type": "FeatureContextConstraint",
          "featureContext": {
            "id": "gene:hgnc:3430",
            "conceptType": "Gene",
            "name": "ERBB2",
            "primaryCoding": {
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              "code": "HGNC:3430",
              "system": "https://genenames.org",
              "iris": [
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              ]
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            "mappings": [
              {
                "relation": "exactMatch",
                "coding": {
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                  "code": "ENSG00000141736",
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                  "iris": [
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              },
              {
                "relation": "exactMatch",
                "coding": {
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                  "system": "https://www.ncbi.nlm.nih.gov/gene",
                  "iris": [
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                  ]
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              },
              {
                "relation": "relatedMatch",
                "coding": {
                  "id": "coding:refseq:NM_004448.4",
                  "code": "NM_004448.4",
                  "system": "https://www.ncbi.nlm.nih.gov/nuccore",
                  "iris": [
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                }
              }
            ]
          }
        },
        {
          "type": "CopyChangeConstraint",
          "copyChange": "gain"
        }
      ],
      "extensions": [
        {
          "name": "biomarker_type",
          "value": "Copy number"
        },
        {
          "name": "cytoband",
          "value": null
        }
      ]
    }
  ]
}