{
  "meta": {
    "data_length": 1,
    "message": "Biomarker id BRIP1 pathogenic variants retrieved successfully",
    "request_url": "http://api.moalmanac.org/biomarkers?biomarker_name=BRIP1+pathogenic+variants",
    "status": "success",
    "status_code": 200,
    "timestamp_elapsed": 0.005135,
    "timestamp_received": "2026-04-09T01:24:15.062689+00:00Z",
    "timestamp_returned": "2026-04-09T01:24:15.067824+00:00Z",
    "trace_id": "cf658329-ed38-4dc9-98f4-88c69a5ab83b"
  },
  "service": {
    "github": "https://github.com/vanallenlab/moalmanac-db",
    "name": "Molecular Oncology Almanac",
    "license": "GPL-2.0",
    "release": "draft",
    "url": "https://dev.moalmanac.org",
    "last_updated": "2026-03-05"
  },
  "data": [
    {
      "id": 6,
      "name": "BRIP1 pathogenic variants",
      "genes": [
        {
          "id": 11,
          "name": "BRIP1",
          "primaryCoding": {
            "id": "hgnc:20473",
            "code": "HGNC:20473",
            "name": null,
            "system": "https://genenames.org",
            "systemVersion": null,
            "iris": [
              "https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:20473"
            ]
          },
          "mappings": [
            {
              "relation": "relatedMatch",
              "coding": {
                "id": "refseq:NM_032043.3",
                "code": "NM_032043.3",
                "name": null,
                "system": "https://www.ncbi.nlm.nih.gov/nuccore",
                "systemVersion": null,
                "iris": [
                  "https://www.ncbi.nlm.nih.gov/nuccore/NM_032043.3"
                ]
              }
            },
            {
              "relation": "exactMatch",
              "coding": {
                "id": "ensembl:ensg00000136492",
                "code": "ENSG00000136492",
                "name": null,
                "system": "https://www.ensembl.org",
                "systemVersion": null,
                "iris": [
                  "https://www.ensembl.org/id/ENSG00000136492"
                ]
              }
            },
            {
              "relation": "exactMatch",
              "coding": {
                "id": "ncbi:83990",
                "code": "83990",
                "name": null,
                "system": "https://www.ncbi.nlm.nih.gov/gene",
                "systemVersion": null,
                "iris": [
                  "https://www.ncbi.nlm.nih.gov/gene/83990"
                ]
              }
            }
          ],
          "extensions": [
            {
              "name": "location",
              "value": "17q23.2"
            },
            {
              "name": "location_sortable",
              "value": "17q23.2"
            }
          ]
        }
      ],
      "type": "CategoricalVariant",
      "extensions": [
        {
          "name": "biomarker_type",
          "value": "Germline Variant"
        },
        {
          "name": "present",
          "value": true
        },
        {
          "name": "chromosome",
          "value": "17"
        },
        {
          "name": "requires_pathogenic",
          "value": true
        }
      ]
    }
  ]
}