{
  "meta": {
    "data_length": 1,
    "message": "Biomarker id IDH2 p.R140W retrieved successfully",
    "request_url": "http://api.moalmanac.org/biomarkers?biomarker_name=IDH2+p.R140W",
    "status": "success",
    "status_code": 200,
    "timestamp_elapsed": 0.00485,
    "timestamp_received": "2026-04-29T23:15:05.606328+00:00Z",
    "timestamp_returned": "2026-04-29T23:15:05.611178+00:00Z",
    "trace_id": "471984ce-1c92-4ff6-bf90-0a42d838ab80"
  },
  "service": {
    "github": "https://github.com/vanallenlab/moalmanac-db",
    "name": "Molecular Oncology Almanac",
    "license": "GPL-2.0",
    "release": "draft",
    "url": "https://dev.moalmanac.org",
    "last_updated": "2026-04-09"
  },
  "data": [
    {
      "id": 110,
      "name": "IDH2 p.R140W",
      "genes": [
        {
          "id": 29,
          "name": "IDH2",
          "primaryCoding": {
            "id": "hgnc:5383",
            "code": "HGNC:5383",
            "name": null,
            "system": "https://genenames.org",
            "systemVersion": null,
            "iris": [
              "https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:5383"
            ]
          },
          "mappings": [
            {
              "relation": "relatedMatch",
              "coding": {
                "id": "refseq:NM_002168.4",
                "code": "NM_002168.4",
                "name": null,
                "system": "https://www.ncbi.nlm.nih.gov/nuccore",
                "systemVersion": null,
                "iris": [
                  "https://www.ncbi.nlm.nih.gov/nuccore/NM_002168.4"
                ]
              }
            },
            {
              "relation": "exactMatch",
              "coding": {
                "id": "ensembl:ensg00000182054",
                "code": "ENSG00000182054",
                "name": null,
                "system": "https://www.ensembl.org",
                "systemVersion": null,
                "iris": [
                  "https://www.ensembl.org/id/ENSG00000182054"
                ]
              }
            },
            {
              "relation": "exactMatch",
              "coding": {
                "id": "ncbi:3418",
                "code": "3418",
                "name": null,
                "system": "https://www.ncbi.nlm.nih.gov/gene",
                "systemVersion": null,
                "iris": [
                  "https://www.ncbi.nlm.nih.gov/gene/3418"
                ]
              }
            }
          ],
          "extensions": [
            {
              "name": "location",
              "value": "15q26.1"
            },
            {
              "name": "location_sortable",
              "value": "15q26.1"
            }
          ]
        }
      ],
      "type": "CategoricalVariant",
      "extensions": [
        {
          "name": "biomarker_type",
          "value": "Somatic Variant"
        },
        {
          "name": "present",
          "value": true
        },
        {
          "name": "chromosome",
          "value": "15"
        },
        {
          "name": "start_position",
          "value": 90631935
        },
        {
          "name": "end_position",
          "value": 90631935
        },
        {
          "name": "reference_allele",
          "value": "G"
        },
        {
          "name": "alternate_allele",
          "value": "A"
        },
        {
          "name": "cdna_change",
          "value": "c.418C>T"
        },
        {
          "name": "protein_change",
          "value": "p.R140W"
        },
        {
          "name": "variant_annotation",
          "value": "Missense"
        },
        {
          "name": "exon",
          "value": "4"
        },
        {
          "name": "rsid",
          "value": "rs267606870"
        },
        {
          "name": "hgvsg",
          "value": "15:g.90631935G>A"
        }
      ]
    }
  ]
}