{
  "meta": {
    "data_length": 1,
    "message": "Biomarker id MLH1 pathogenic variants retrieved successfully",
    "request_url": "http://api.moalmanac.org/biomarkers?biomarker_name=MLH1+pathogenic+variants",
    "status": "success",
    "status_code": 200,
    "timestamp_elapsed": 0.005021,
    "timestamp_received": "2026-04-24T15:54:19.334960+00:00Z",
    "timestamp_returned": "2026-04-24T15:54:19.339981+00:00Z",
    "trace_id": "8e4502d0-9ba6-435d-8cde-ac3f85000e46"
  },
  "service": {
    "github": "https://github.com/vanallenlab/moalmanac-db",
    "name": "Molecular Oncology Almanac",
    "license": "GPL-2.0",
    "release": "draft",
    "url": "https://dev.moalmanac.org",
    "last_updated": "2026-04-09"
  },
  "data": [
    {
      "id": 165,
      "name": "MLH1 pathogenic variants",
      "genes": [
        {
          "id": 58,
          "name": "MLH1",
          "primaryCoding": {
            "id": "hgnc:7127",
            "code": "HGNC:7127",
            "name": null,
            "system": "https://genenames.org",
            "systemVersion": null,
            "iris": [
              "https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7127"
            ]
          },
          "mappings": [
            {
              "relation": "exactMatch",
              "coding": {
                "id": "ensembl:ensg00000076242",
                "code": "ENSG00000076242",
                "name": null,
                "system": "https://www.ensembl.org",
                "systemVersion": null,
                "iris": [
                  "https://www.ensembl.org/id/ENSG00000076242"
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              }
            },
            {
              "relation": "exactMatch",
              "coding": {
                "id": "ncbi:4292",
                "code": "4292",
                "name": null,
                "system": "https://www.ncbi.nlm.nih.gov/gene",
                "systemVersion": null,
                "iris": [
                  "https://www.ncbi.nlm.nih.gov/gene/4292"
                ]
              }
            },
            {
              "relation": "relatedMatch",
              "coding": {
                "id": "refseq:NM_000249.4",
                "code": "NM_000249.4",
                "name": null,
                "system": "https://www.ncbi.nlm.nih.gov/nuccore",
                "systemVersion": null,
                "iris": [
                  "https://www.ncbi.nlm.nih.gov/nuccore/NM_000249.4"
                ]
              }
            }
          ],
          "extensions": [
            {
              "name": "location",
              "value": "3p22.2"
            },
            {
              "name": "location_sortable",
              "value": "03p22.2"
            }
          ]
        }
      ],
      "type": "CategoricalVariant",
      "extensions": [
        {
          "name": "biomarker_type",
          "value": "Germline Variant"
        },
        {
          "name": "present",
          "value": true
        },
        {
          "name": "chromosome",
          "value": "3"
        },
        {
          "name": "requires_pathogenic",
          "value": true
        }
      ]
    }
  ]
}