{
  "meta": {
    "data_length": 1,
    "message": "Biomarker id NPM1 p.W288Cfs*12 retrieved successfully",
    "request_url": "http://api.moalmanac.org/biomarkers?biomarker_name=NPM1+p.W288Cfs%2A12",
    "status": "success",
    "status_code": 200,
    "timestamp_elapsed": 0.004881,
    "timestamp_received": "2026-04-09T01:29:23.558994+00:00Z",
    "timestamp_returned": "2026-04-09T01:29:23.563875+00:00Z",
    "trace_id": "80e8041b-0a46-49ce-abda-07a003bb6e9c"
  },
  "service": {
    "github": "https://github.com/vanallenlab/moalmanac-db",
    "name": "Molecular Oncology Almanac",
    "license": "GPL-2.0",
    "release": "draft",
    "url": "https://dev.moalmanac.org",
    "last_updated": "2026-03-05"
  },
  "data": [
    {
      "id": 177,
      "name": "NPM1 p.W288Cfs*12",
      "genes": [
        {
          "id": 62,
          "name": "NPM1",
          "primaryCoding": {
            "id": "hgnc:7910",
            "code": "HGNC:7910",
            "name": "NPM1",
            "system": "https://genenames.org",
            "systemVersion": null,
            "iris": [
              "https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7910"
            ]
          },
          "mappings": [
            {
              "relation": "relatedMatch",
              "coding": {
                "id": "refseq:NM_002520.7",
                "code": "NM_002520.7",
                "name": null,
                "system": "https://www.ncbi.nlm.nih.gov/nuccore",
                "systemVersion": null,
                "iris": [
                  "https://www.ncbi.nlm.nih.gov/nuccore/NM_002520.7"
                ]
              }
            },
            {
              "relation": "relatedMatch",
              "coding": {
                "id": "ensembl:ensg00000181163",
                "code": "ENSG00000181163",
                "name": null,
                "system": "https://www.ensembl.org",
                "systemVersion": null,
                "iris": [
                  "https://www.ensembl.org/id/ENSG00000181163"
                ]
              }
            },
            {
              "relation": "relatedMatch",
              "coding": {
                "id": "ncbi:4869",
                "code": "4869",
                "name": null,
                "system": "https://www.ncbi.nlm.nih.gov/gene",
                "systemVersion": null,
                "iris": [
                  "https://www.ncbi.nlm.nih.gov/gene/4869"
                ]
              }
            }
          ],
          "extensions": [
            {
              "name": "location",
              "value": "5q35.1"
            },
            {
              "name": "location_sortable",
              "value": "05q35.1"
            }
          ]
        }
      ],
      "type": "CategoricalVariant",
      "extensions": [
        {
          "name": "biomarker_type",
          "value": "Somatic Variant"
        },
        {
          "name": "present",
          "value": true
        },
        {
          "name": "chromosome",
          "value": "5"
        },
        {
          "name": "start_position",
          "value": 171410544
        },
        {
          "name": "end_position",
          "value": 171410543
        },
        {
          "name": "reference_allele",
          "value": "-"
        },
        {
          "name": "alternate_allele",
          "value": "TCTG"
        },
        {
          "name": "cdna_change",
          "value": "c.860_863dup"
        },
        {
          "name": "protein_change",
          "value": "p.W288Cfs*12"
        },
        {
          "name": "variant_annotation",
          "value": "Frameshift"
        },
        {
          "name": "exon",
          "value": "11/11"
        },
        {
          "name": "rsid",
          "value": "rs587776806"
        },
        {
          "name": "hgvsg",
          "value": "5:g.171410540_171410543dup"
        }
      ]
    }
  ]
}