{
  "meta": {
    "data_length": 1,
    "message": "Biomarker id PIK3CA amplification retrieved successfully",
    "request_url": "http://api.moalmanac.org/biomarkers?biomarker_name=PIK3CA+amplification",
    "status": "success",
    "status_code": 200,
    "timestamp_elapsed": 0.009581,
    "timestamp_received": "2026-04-23T19:07:48.273564+00:00Z",
    "timestamp_returned": "2026-04-23T19:07:48.283145+00:00Z",
    "trace_id": "6065cece-5f3b-4964-bf2b-6f534c027d95"
  },
  "service": {
    "github": "https://github.com/vanallenlab/moalmanac-db",
    "name": "Molecular Oncology Almanac",
    "license": "GPL-2.0",
    "release": "draft",
    "url": "https://dev.moalmanac.org",
    "last_updated": "2026-04-09"
  },
  "data": [
    {
      "id": 88,
      "name": "PIK3CA amplification",
      "genes": [
        {
          "id": 41,
          "name": "PIK3CA",
          "primaryCoding": {
            "id": "hgnc:8975",
            "code": "HGNC:8975",
            "name": null,
            "system": "https://genenames.org",
            "systemVersion": null,
            "iris": [
              "https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:8975"
            ]
          },
          "mappings": [
            {
              "relation": "relatedMatch",
              "coding": {
                "id": "refseq:NM_006218.4",
                "code": "NM_006218.4",
                "name": null,
                "system": "https://www.ncbi.nlm.nih.gov/nuccore",
                "systemVersion": null,
                "iris": [
                  "https://www.ncbi.nlm.nih.gov/nuccore/NM_006218.4"
                ]
              }
            },
            {
              "relation": "exactMatch",
              "coding": {
                "id": "ensembl:ensg00000121879",
                "code": "ENSG00000121879",
                "name": null,
                "system": "https://www.ensembl.org",
                "systemVersion": null,
                "iris": [
                  "https://www.ensembl.org/id/ENSG00000121879"
                ]
              }
            },
            {
              "relation": "exactMatch",
              "coding": {
                "id": "ncbi:5290",
                "code": "5290",
                "name": null,
                "system": "https://www.ncbi.nlm.nih.gov/gene",
                "systemVersion": null,
                "iris": [
                  "https://www.ncbi.nlm.nih.gov/gene/5290"
                ]
              }
            }
          ],
          "extensions": [
            {
              "name": "location",
              "value": "3q26.32"
            },
            {
              "name": "location_sortable",
              "value": "03q26.32"
            }
          ]
        }
      ],
      "type": "CategoricalVariant",
      "extensions": [
        {
          "name": "biomarker_type",
          "value": "Copy Number"
        },
        {
          "name": "present",
          "value": true
        },
        {
          "name": "direction",
          "value": "Amplification"
        }
      ]
    }
  ]
}