{
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    "timestamp_received": "2026-04-24T03:26:16.523223+00:00Z",
    "timestamp_returned": "2026-04-24T03:26:16.527399+00:00Z",
    "trace_id": "771e280e-d0dc-4227-9c43-e8e62c4c61d1"
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  "service": {
    "github": "https://github.com/vanallenlab/moalmanac-db",
    "name": "Molecular Oncology Almanac",
    "license": "GPL-2.0",
    "release": "draft",
    "url": "https://dev.moalmanac.org",
    "last_updated": "2026-04-09"
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  "data": [
    {
      "id": "ind:ema.blincyto:1",
      "indication": "BLINCYTO is indicated as monotherapy for the treatment of adults with Philadelphia chromosome-negative CD19 positive B-cell precursor ALL in first or second complete remission with minimal residual disease (MRD) greater than or equal to 0.1%.",
      "initial_approval_date": "2019-02-26",
      "initial_approval_url": "https://www.ema.europa.eu/en/documents/variation-report/blincyto-h-c-3731-ii-0011-epar-assessment-report-variation_en.pdf",
      "description": "The European Medicines Agency (EMA) has authorized Blincyto (blinatumomab) as a monotherapy for the treatment of adult patients with Philadelphia chromosome negative CD19 positive B-cell precusor ALL in first or second complete remission with minimal residual disease (MRD) greater than or equal to 0.1%.",
      "raw_biomarkers": "Philadelphia chromosome negative CD19 positive",
      "raw_cancer_type": "Acute lymphoblastic leukemia (ALL)",
      "raw_therapeutics": "Blincyto (blinatumomab)",
      "icd10": null,
      "regimen_code": null,
      "reimbursement_category": null,
      "reimbursement_date": null,
      "reimbursement_details": null,
      "date_regular_approval": null,
      "date_accelerated_approval": null,
      "document": {
        "id": "doc:ema.blincyto",
        "type": "Document",
        "documentType": "Regulatory approval",
        "name": "Blincyto (blinatumomab) [product information]. EMA.",
        "title": null,
        "aliases": [],
        "description": "Amgen Europe B.V. Blincyto (blinatumomab) [product information]. European Medicines Agency website. https://www.ema.europa.eu/en/documents/product-information/blincyto-epar-product-information_en.pdf. Revised July 2025. Accessed August 29, 2025.",
        "urls": [
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        ],
        "doi": null,
        "pmid": null,
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              "id": "ema",
              "type": "Agent",
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              "name": "European Medicines Agency",
              "description": "Regulatory agency that approves medicines for use in the European Union.",
              "extensions": [
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                  "name": "last_updated",
                  "value": "2025-10-01",
                  "description": ""
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                  "name": "url",
                  "value": "https://www.ema.europa.eu/en/medicines",
                  "description": ""
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            "description": "The organization that published this document."
          },
          {
            "name": "company",
            "value": "Amgen Europe B.V.",
            "description": "The company that manufactures the cancer drug. Only applicable to market authorization documents."
          },
          {
            "name": "drug_name_brand",
            "value": "Blincyto",
            "description": "The brand name of the cancer drug, per this document. Only applicable to market authorization documents."
          },
          {
            "name": "drug_name_generic",
            "value": "blinatumomab",
            "description": "The generic name of the cancer drug, per this document. Only applicable to market authorization documents."
          },
          {
            "name": "first_publication_date",
            "value": "2015-12-07",
            "description": "The publication date for the initial version of this document."
          },
          {
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            "value": null,
            "description": "Identification number used by the publishing organization."
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          {
            "name": "publication_date",
            "value": "2025-07-23",
            "description": "The publication date for the document."
          },
          {
            "name": "status",
            "value": "Active",
            "description": "Whether this document is Active or Deprecated within moalmanac-db."
          }
        ]
      }
    }
  ]
}