{
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    "message": "Indication id ind:ema.bosulif:1 retrieved successfully",
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    "timestamp_received": "2026-04-24T03:11:14.807865+00:00Z",
    "timestamp_returned": "2026-04-24T03:11:14.812090+00:00Z",
    "trace_id": "d2e5e9d9-fb9b-4f8a-9da4-dd728826c0de"
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    "github": "https://github.com/vanallenlab/moalmanac-db",
    "name": "Molecular Oncology Almanac",
    "license": "GPL-2.0",
    "release": "draft",
    "url": "https://dev.moalmanac.org",
    "last_updated": "2026-04-09"
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  "data": [
    {
      "id": "ind:ema.bosulif:1",
      "indication": "Bosulif is indicated for the treatment of adult patients with accelerated phase (AP), and blast phase (BP) Ph+ CML previously treated with one or more tyrosine kinase inhibitor(s) [TKI(s)] and for whom imatinib, nilotinib and dasatinib are not considered appropriate treatment options.",
      "initial_approval_date": "2025-08-26",
      "initial_approval_url": "https://www.ema.europa.eu/en/documents/variation-report/bosulif-h-c-002373-x-0058-g-epar-assessment-report-variation_en.pdf",
      "description": "The European Medicines Agency (EMA) has authorized bosutinib as for the treatment of adult patients with accelerated phase, and blast phase Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML) previously treated with one or more tyrosine kinase inhibitors and for whom imatinib, nilotinib, and dasatinib are not considered appropriate treatment options.",
      "raw_biomarkers": "Philadelphia chromosome-positive",
      "raw_cancer_type": "Chronic Myelogenous Leukemia",
      "raw_therapeutics": "Bosulif (bosutinib)",
      "icd10": null,
      "regimen_code": null,
      "reimbursement_category": null,
      "reimbursement_date": null,
      "reimbursement_details": null,
      "date_regular_approval": null,
      "date_accelerated_approval": null,
      "document": {
        "id": "doc:ema.bosulif",
        "type": "Document",
        "documentType": "Regulatory approval",
        "name": "Bosulif (bosutinib) [product information]. EMA.",
        "title": null,
        "aliases": [],
        "description": "Pfizer Europe MA EEIG. Bosulif (bosutinib) [product information]. European Medicines Agency website. https://www.ema.europa.eu/en/documents/product-information/bosulif-epar-product-information_en.pdf. Revised August 2025. Accessed August 29, 2025.",
        "urls": [
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        ],
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        "pmid": null,
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              "extensions": [
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                  "description": ""
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          {
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            "value": "Pfizer Europe MA EEIG.",
            "description": "The company that manufactures the cancer drug. Only applicable to market authorization documents."
          },
          {
            "name": "drug_name_brand",
            "value": "Bosulif",
            "description": "The brand name of the cancer drug, per this document. Only applicable to market authorization documents."
          },
          {
            "name": "drug_name_generic",
            "value": "bosutinib",
            "description": "The generic name of the cancer drug, per this document. Only applicable to market authorization documents."
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          {
            "name": "first_publication_date",
            "value": "2013-04-09",
            "description": "The publication date for the initial version of this document."
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            "value": null,
            "description": "Identification number used by the publishing organization."
          },
          {
            "name": "publication_date",
            "value": "2025-08-26",
            "description": "The publication date for the document."
          },
          {
            "name": "status",
            "value": "Active",
            "description": "Whether this document is Active or Deprecated within moalmanac-db."
          }
        ]
      }
    }
  ]
}