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    "timestamp_received": "2026-04-24T16:04:14.043357+00:00Z",
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    "name": "Molecular Oncology Almanac",
    "license": "GPL-2.0",
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    "url": "https://dev.moalmanac.org",
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  "data": [
    {
      "id": "ind:ema.tagrisso:4",
      "indication": "TAGRISSO as a monotherapy is indicated for the treatment of adult patients with locally advanced, unresectable NSCLC whose tumours have EGFR exon 19 deletions or exon 21 (L858R) substitution mutations and whose disease has not progressed during or following platinum-based chemoradiation therapy.",
      "initial_approval_date": "2025-01-09",
      "initial_approval_url": "https://www.ema.europa.eu/en/documents/product-information/tagrisso-epar-product-information_en.pdf",
      "description": "The European Medicines Agency (EMA) has authorized osimertinib for the treatment of adult patients with locally advanced, unresectable non-small cell lung cancer (NSCLC) whose tumors have EGFR exon 19 deletions or exon 21 (L858R) substitution mutations and whose disease has not progressed during or following platinum-based chemoradiation therapy.",
      "raw_biomarkers": "EGFR exon 19 deletions or exon 21 (L858R)",
      "raw_cancer_type": "Non-small cell lung cancer",
      "raw_therapeutics": "Tagrisso (osimertinib)",
      "icd10": null,
      "regimen_code": null,
      "reimbursement_category": null,
      "reimbursement_date": null,
      "reimbursement_details": null,
      "date_regular_approval": null,
      "date_accelerated_approval": null,
      "document": {
        "id": "doc:ema.tagrisso",
        "type": "Document",
        "documentType": "Regulatory approval",
        "name": "Tagrisso (osimertinib) [product information]. EMA.",
        "title": null,
        "aliases": [],
        "description": "AstraZeneca AB. Tagrisso (osimertinib) [product information]. European Medicines Agency website. https://www.ema.europa.eu/en/documents/product-information/tagrisso-epar-product-information_en.pdf. Revised January 2025. Accessed September 5, 2025.",
        "urls": [
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        "pmid": null,
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                  "description": ""
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            "name": "company",
            "value": "AstraZeneca AB.",
            "description": "The company that manufactures the cancer drug. Only applicable to market authorization documents."
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          {
            "name": "drug_name_brand",
            "value": "Tagrisso",
            "description": "The brand name of the cancer drug, per this document. Only applicable to market authorization documents."
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            "name": "drug_name_generic",
            "value": "osimertinib",
            "description": "The generic name of the cancer drug, per this document. Only applicable to market authorization documents."
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          {
            "name": "first_publication_date",
            "value": "2016-02-17",
            "description": "The publication date for the initial version of this document."
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            "value": null,
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            "value": "2025-09-05",
            "description": "The publication date for the document."
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            "name": "status",
            "value": "Active",
            "description": "Whether this document is Active or Deprecated within moalmanac-db."
          }
        ]
      }
    }
  ]
}