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    "name": "Molecular Oncology Almanac",
    "license": "GPL-2.0",
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  "data": [
    {
      "id": "ind:ema.tarceva:0",
      "indication": "Tarceva is indicated for the first-line treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with EGFR activating mutations.",
      "initial_approval_date": "2011-11-14",
      "initial_approval_url": "https://www.ema.europa.eu/en/documents/variation-report/tarceva-h-c-618-ii-0020-epar-assessment-report-variation_en.pdf",
      "description": "The European Medicines Agency (EMA) has authorized erlotinib for the first-line treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with EGFR activating variants. Erlotinib's production information further states that factors associated with prolonged survival should be taken into account when prescribing erlotinib. It further states that no survival benefit or other clinically relevant effects of the treatment have been demonstrated in patients with Epidermal Growth Factor Receptor (EGFR)-IHC negative tumors.",
      "raw_biomarkers": null,
      "raw_cancer_type": "Non-small cell lung cancer",
      "raw_therapeutics": "Tarceva (erlotinib)",
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      "document": {
        "id": "doc:ema.tarceva",
        "type": "Document",
        "documentType": "Regulatory approval",
        "name": "Tarceva (erlotinib) [product information]. EMA.",
        "title": null,
        "aliases": [],
        "description": "Roche Registration GmbH. Tarceva (erlotinib) [product information]. European Medicines Agency website. https://www.ema.europa.eu/en/documents/product-information/tarceva-epar-product-information_en.pdf. Revised May 2023. Accessed March 23, 2024.",
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            "description": "The company that manufactures the cancer drug. Only applicable to market authorization documents."
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            "description": "The brand name of the cancer drug, per this document. Only applicable to market authorization documents."
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            "description": "The generic name of the cancer drug, per this document. Only applicable to market authorization documents."
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}