{
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    "timestamp_received": "2026-09-25T00:12:18.199604+00:00Z",
    "timestamp_returned": "2026-09-25T00:12:18.201803+00:00Z",
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    "name": "Molecular Oncology Almanac",
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    "release": "draft",
    "url": "https://dev.moalmanac.org",
    "last_updated": "2026-08-02"
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  "data": [
    {
      "id": "ind:fda:modeyso:0",
      "type": "Indication",
      "description": "MODEYSO is a protease activator indicated for the treatment of adult and pediatric patients 1 year of age and older with diffuse midline glioma harboring an H3 K27M mutation with progressive disease following prior therapy.",
      "contributions": [
        {
          "id": "ctrb:vanallenlab:2025-10-02:0",
          "type": "Contribution",
          "description": "On 2025-08-06, the US FDA granted accelerated approval to Modeyso (dordaviprone) for the treatment of adult and pediatric patients 1 year of age and older with diffuse midline glioma harboring an H3 K27M mutation with progressive disease following prior therapy.",
          "date": "2025-10-02",
          "contributor": {
            "id": "agent:user:vanallenlab",
            "type": "Agent",
            "agentType": "contributor",
            "name": "Van Allen lab",
            "description": "Van Allen lab, Dana-Farber Cancer Institute"
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        {
          "id": "ctrb:fda:2025-08-06:0",
          "type": "Contribution",
          "description": "Indication received accelerated approval.",
          "date": "2025-08-06",
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            "type": "Agent",
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            "name": "Food and Drug Administration",
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          "id": "doc:fda:modeyso",
          "type": "Document",
          "documentType": "Regulatory approval",
          "name": "Modeyso (dordaviprone) [package insert]. FDA.",
          "title": null,
          "aliases": [],
          "description": "Chimerix, Inc. Modeyso (dordaviprone) [package insert]. U.S. Food and Drug Administration website. https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/219876s000lbl.pdf. Revised August 2025. Accessed October 2, 2025.",
          "urls": [
            "https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/219876s000lbl.pdf",
            "https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=219876"
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          "pmid": null,
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              "description": "The organization that published this document."
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            {
              "name": "company",
              "value": "Chimerix, Inc.",
              "description": "The company that manufactures the cancer drug. Only applicable to market authorization documents."
            },
            {
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              "value": "Modeyso",
              "description": "The brand name of the cancer drug, per this document. Only applicable to market authorization documents."
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              "value": "dordaviprone",
              "description": "The generic name of the cancer drug, per this document. Only applicable to market authorization documents."
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              "value": "2025-08-06",
              "description": "The publication date for the initial version of this document."
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              "value": 219876,
              "description": "Identification number used by the publishing organization."
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              "value": "2025-08-06",
              "description": "The publication date for the document."
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            {
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              "value": "Active",
              "description": "Whether this document is Active or Deprecated within moalmanac-db."
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          "value": "Accelerated",
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}