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    "name": "Molecular Oncology Almanac",
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  "data": [
    {
      "id": "ind:fda.afinitor:2",
      "indication": "AFINITOR and AFINITOR DISPERZ are kinase inhibitors indicated for the treatment of adult and pediatric patients aged 1 year and older with TSC who have subependymal giant cell astrocytoma (SEGA) that requires therapeutic intervention but cannot be curatively resected.",
      "initial_approval_date": "2010-10-29",
      "initial_approval_url": "https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/022334s032,203985s010lbl.pdf",
      "description": "The U.S. Food and Drug Administration granted approval to everolimus for the treatment of adult and pediatric patients aged 1 year and older with TSC who have subependymal giant cell astrocytoma (SEGA) that requires therapeutic intervention but cannot be curatively resected.",
      "raw_biomarkers": "TSC1/2",
      "raw_cancer_type": "subependymal giant cell astrocytoma",
      "raw_therapeutics": "everolimus",
      "icd10": null,
      "regimen_code": null,
      "reimbursement_category": null,
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      "reimbursement_details": null,
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        "id": "doc:fda.afinitor",
        "type": "Document",
        "documentType": "Regulatory approval",
        "name": "Afinitor (everolimus) [package insert]. FDA.",
        "title": null,
        "aliases": [],
        "description": "Novartis Pharmaceuticals Corporation. Afinitor (everolimus) [package insert]. U.S. Food and Drug Administration website. https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/203985s023,022334s051lbl.pdf. Revised February 2022. Accessed October 30, 2024.",
        "urls": [
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            "description": "The company that manufactures the cancer drug. Only applicable to market authorization documents."
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            "description": "The brand name of the cancer drug, per this document. Only applicable to market authorization documents."
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            "description": "The generic name of the cancer drug, per this document. Only applicable to market authorization documents."
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}