{
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    "message": "Indication id ind:fda.yervoy:0 retrieved successfully",
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    "timestamp_received": "2026-04-06T14:48:18.909578+00:00Z",
    "timestamp_returned": "2026-04-06T14:48:18.914182+00:00Z",
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  "service": {
    "github": "https://github.com/vanallenlab/moalmanac-db",
    "name": "Molecular Oncology Almanac",
    "license": "GPL-2.0",
    "release": "draft",
    "url": "https://dev.moalmanac.org",
    "last_updated": "2026-03-05"
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  "data": [
    {
      "id": "ind:fda.yervoy:0",
      "indication": "YERVOY is a human cytotoxic T-lymphocyte antigen 4 (CTLA-4)-blocking antibody indicated for treatment of adult and pediatric patients 12 years and older with unresectable or metastatic microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) colorectal cancer in combination with nivolumab.",
      "initial_approval_date": "2018-07-10",
      "initial_approval_url": "https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/125377s096lbl.pdf",
      "description": "The U.S. Food and Drug Administration granted approval to ipilimumab in combination with nivolumab for the treatment of adult and pediatric patients 12 years and older with unresectable or metastatic microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) colorectal cancer in combination with nivolumab.",
      "raw_biomarkers": "microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR)",
      "raw_cancer_type": "metastatic colorectal cancer",
      "raw_therapeutics": "Yervoy (ipilimumab) in combination with nivolumab",
      "icd10": null,
      "regimen_code": null,
      "reimbursement_category": null,
      "reimbursement_date": null,
      "reimbursement_details": null,
      "date_regular_approval": "2025-04-08",
      "date_accelerated_approval": "2018-07-10",
      "document": {
        "id": "doc:fda.yervoy",
        "type": "Document",
        "documentType": "Regulatory approval",
        "name": "Yervoy (ipilimumab) [package insert]. FDA.",
        "title": null,
        "aliases": [],
        "description": "Bristol-Myers Squibb Company. Yervoy (ipilimumab) [package insert]. U.S. Food and Drug Administration website. https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/125377s133lbl.pdf. Revised April 2025. Accessed April 30, 2025.",
        "urls": [
          "https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/125377s133lbl.pdf",
          "https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=125377"
        ],
        "doi": null,
        "pmid": null,
        "extensions": [
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              "agentType": "organization",
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              "extensions": [
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                  "name": "last_updated",
                  "value": "2026-03-02",
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            "description": "The organization that published this document."
          },
          {
            "name": "company",
            "value": "Bristol-Myers Squibb Company.",
            "description": "The company that manufactures the cancer drug. Only applicable to market authorization documents."
          },
          {
            "name": "drug_name_brand",
            "value": "Yervoy",
            "description": "The brand name of the cancer drug, per this document. Only applicable to market authorization documents."
          },
          {
            "name": "drug_name_generic",
            "value": "ipilimumab",
            "description": "The generic name of the cancer drug, per this document. Only applicable to market authorization documents."
          },
          {
            "name": "first_publication_date",
            "value": "2011-03-25",
            "description": "The publication date for the initial version of this document."
          },
          {
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            "value": 125377,
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            "name": "publication_date",
            "value": "2025-04-11",
            "description": "The publication date for the document."
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          {
            "name": "status",
            "value": "Active",
            "description": "Whether this document is Active or Deprecated within moalmanac-db."
          }
        ]
      }
    }
  ]
}