{
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    "request_url": "http://api.moalmanac.org/indications?indication_id=ind%3Ahc%3Aiclusig%3A1",
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    "timestamp_received": "2026-09-25T00:13:29.908007+00:00Z",
    "timestamp_returned": "2026-09-25T00:13:29.909595+00:00Z",
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    "name": "Molecular Oncology Almanac",
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    "url": "https://dev.moalmanac.org",
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      "id": "ind:hc:iclusig:1",
      "type": "Indication",
      "description": "ICLUSIG (ponatinib tablets) is indicated for the treatment of adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL) for whom other tyrosine kinase inhibitor (TKI) therapy is not appropriate, including Ph+ ALL that is T315I mutation positive or where there is prior TKI resistance or intolerance",
      "contributions": [
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          "id": "ctrb:vanallenlab:2024-10-30:0",
          "type": "Contribution",
          "description": "Initial access of FDA approvals",
          "date": "2024-10-30",
          "contributor": {
            "id": "agent:user:vanallenlab",
            "type": "Agent",
            "agentType": "contributor",
            "name": "Van Allen lab",
            "description": "Van Allen lab, Dana-Farber Cancer Institute"
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          "id": "doc:hc:iclusig",
          "type": "Document",
          "documentType": "Regulatory approval",
          "name": "Iclusig (ponatinib) [product monograph]. HC.",
          "title": null,
          "aliases": [],
          "description": "Takeda Pharmaceuticals U.S.A., Inc. Iclusig (ponatinib) [product monograph]. Health Canada website. https://pdf.hres.ca/dpd_pm/00078669.PDF. Revised February. Accessed June 2025.",
          "urls": [
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            "https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=92168"
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              "value": "Takeda Pharmaceuticals U.S.A., Inc.",
              "description": "The company that manufactures the cancer drug. Only applicable to market authorization documents."
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              "value": "Iclusig",
              "description": "The brand name of the cancer drug, per this document. Only applicable to market authorization documents."
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              "description": "The publication date for the document."
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              "description": "Whether this document is Active or Deprecated within moalmanac-db."
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          "value": "Approved",
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