{
  "meta": {
    "data_length": 1,
    "message": "Indication id ind:hc:kadcyla:1 retrieved successfully",
    "request_url": "http://api.moalmanac.org/indications?indication_id=ind%3Ahc%3Akadcyla%3A1",
    "status": "success",
    "status_code": 200,
    "timestamp_elapsed": 0.001619,
    "timestamp_received": "2026-09-25T01:16:27.593699+00:00Z",
    "timestamp_returned": "2026-09-25T01:16:27.595318+00:00Z",
    "trace_id": "42d3d008-e17a-4b0a-bf15-16917b31fe06"
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  "service": {
    "github": "https://github.com/vanallenlab/moalmanac-db",
    "name": "Molecular Oncology Almanac",
    "license": "GPL-2.0",
    "release": "draft",
    "url": "https://dev.moalmanac.org",
    "last_updated": "2026-08-02"
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  "data": [
    {
      "id": "ind:hc:kadcyla:1",
      "type": "Indication",
      "description": "KADCYLA monotherapy indicated for the adjuvant treatment of HER2-positive early breast cancer patients who have residual invasive disease following neoadjuvant taxane and trastuzumab-based treatment.",
      "contributions": [
        {
          "id": "ctrb:vanallenlab:2024-10-30:0",
          "type": "Contribution",
          "description": "Initial access of FDA approvals",
          "date": "2024-10-30",
          "contributor": {
            "id": "agent:user:vanallenlab",
            "type": "Agent",
            "agentType": "contributor",
            "name": "Van Allen lab",
            "description": "Van Allen lab, Dana-Farber Cancer Institute"
          }
        }
      ],
      "reportedIn": [
        {
          "id": "doc:hc:kadcyla",
          "type": "Document",
          "documentType": "Regulatory approval",
          "name": "Kadcyla (ado-trastuzumab emtansine) [product monograph]. HC.",
          "title": null,
          "aliases": [],
          "description": "Hoffmann-La Roche Limited. Kadcyla (ado-trastuzumab emtansine) [product monograph]. Health Canada website. https://pdf.hres.ca/dpd_pm/00067729.PDF. Revised October 2022. Accessed June 2025.",
          "urls": [
            "https://pdf.hres.ca/dpd_pm/00067729.PDF",
            "https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=89698"
          ],
          "doi": null,
          "pmid": null,
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                "name": "Health Canada",
                "description": "Regulatory agency that approves drugs for sale and use in Canada."
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              "description": "The organization that published this document."
            },
            {
              "name": "company",
              "value": "Hoffmann-La Roche Limited",
              "description": "The company that manufactures the cancer drug. Only applicable to market authorization documents."
            },
            {
              "name": "drug_name_brand",
              "value": "Kadcyla",
              "description": "The brand name of the cancer drug, per this document. Only applicable to market authorization documents."
            },
            {
              "name": "drug_name_generic",
              "value": "ado-trastuzumab emtansine",
              "description": "The generic name of the cancer drug, per this document. Only applicable to market authorization documents."
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            {
              "name": "first_publication_date",
              "value": "2013-09-11",
              "description": "The publication date for the initial version of this document."
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              "value": null,
              "description": "Identification number used by the publishing organization."
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              "name": "publication_date",
              "value": "2022-10-13",
              "description": "The publication date for the document."
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            {
              "name": "status",
              "value": "Active",
              "description": "Whether this document is Active or Deprecated within moalmanac-db."
            }
          ]
        }
      ],
      "extensions": [
        {
          "name": "status",
          "value": "Approved",
          "description": "Current approval status."
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}