{
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    "message": "Indication id ind:hc.rybrevant:2 retrieved successfully",
    "request_url": "http://api.moalmanac.org/indications?indication_id=ind%3Ahc.rybrevant%3A2",
    "status": "success",
    "status_code": 200,
    "timestamp_elapsed": 0.003575,
    "timestamp_received": "2026-04-06T14:45:02.971053+00:00Z",
    "timestamp_returned": "2026-04-06T14:45:02.974628+00:00Z",
    "trace_id": "3c460f7c-8c45-47f4-95ed-e1a772bdfbf3"
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  "service": {
    "github": "https://github.com/vanallenlab/moalmanac-db",
    "name": "Molecular Oncology Almanac",
    "license": "GPL-2.0",
    "release": "draft",
    "url": "https://dev.moalmanac.org",
    "last_updated": "2026-03-05"
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  "data": [
    {
      "id": "ind:hc.rybrevant:2",
      "indication": "RYBREVANT (amivantamab for injection) is indicated as monotherapy for the treatment of adult patients with locally advanced or metastatic NSCLC with activating EGFR Exon 20 insertion mutations whose disease has progressed on or after platinum-based chemotherapy.",
      "initial_approval_date": null,
      "initial_approval_url": null,
      "description": "Health Canada approved amivantamab as monotherapy for the treatment of adult patients with locally advanced or metastatic NSCLC with activating EGFR Exon 20 insertion mutations whose disease has progressed on or after platinum-based chemotherapy.",
      "raw_biomarkers": "EGFR Exon 20 insertion mutations",
      "raw_cancer_type": "locally advanced or metastatic non-small cell lung cancer (NSCLC)",
      "raw_therapeutics": "Rybrevant (amivantamab)",
      "icd10": null,
      "regimen_code": null,
      "reimbursement_category": null,
      "reimbursement_date": null,
      "reimbursement_details": null,
      "date_regular_approval": null,
      "date_accelerated_approval": null,
      "document": {
        "id": "doc:hc.rybrevant",
        "type": "Document",
        "documentType": "Regulatory approval",
        "name": "Rybrevant (amivantamab-vmjw) [product monograph]. HC.",
        "title": null,
        "aliases": [],
        "description": "Janssen Inc. Rybrevant (amivantamab-vmjw) [product monograph]. Health Canada website. https://pdf.hres.ca/dpd_pm/00078295.PDF. Revised January 2025. Accessed June 2025.",
        "urls": [
          "https://health-products.canada.ca/dpd-bdpp/info?lang=eng&code=101529",
          "https://pdf.hres.ca/dpd_pm/00078295.PDF"
        ],
        "doi": null,
        "pmid": null,
        "extensions": [
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            "value": {
              "id": "hc",
              "type": "Agent",
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              "description": "Regulatory agency that approves drugs for sale and use in Canada.",
              "extensions": [
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                  "name": "last_updated",
                  "value": "2025-06-11",
                  "description": ""
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                  "name": "url",
                  "value": "https://health-products.canada.ca/dpd-bdpp/",
                  "description": ""
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            },
            "description": "The organization that published this document."
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          {
            "name": "company",
            "value": "Janssen Inc.",
            "description": "The company that manufactures the cancer drug. Only applicable to market authorization documents."
          },
          {
            "name": "drug_name_brand",
            "value": "Rybrevant",
            "description": "The brand name of the cancer drug, per this document. Only applicable to market authorization documents."
          },
          {
            "name": "drug_name_generic",
            "value": "amivantamab-vmjw",
            "description": "The generic name of the cancer drug, per this document. Only applicable to market authorization documents."
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          {
            "name": "first_publication_date",
            "value": "2022-03-30",
            "description": "The publication date for the initial version of this document."
          },
          {
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            "value": null,
            "description": "Identification number used by the publishing organization."
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          {
            "name": "publication_date",
            "value": "2025-01-13",
            "description": "The publication date for the document."
          },
          {
            "name": "status",
            "value": "Active",
            "description": "Whether this document is Active or Deprecated within moalmanac-db."
          }
        ]
      }
    }
  ]
}