{
  "meta": {
    "data_length": 1,
    "message": "Indication id ind:hpra.femara:0 retrieved successfully",
    "request_url": "http://api.moalmanac.org/indications?indication_id=ind%3Ahpra.femara%3A0",
    "status": "success",
    "status_code": 200,
    "timestamp_elapsed": 0.00415,
    "timestamp_received": "2026-04-25T13:02:38.500644+00:00Z",
    "timestamp_returned": "2026-04-25T13:02:38.504794+00:00Z",
    "trace_id": "dd1c5a5c-40c7-4e49-97bd-b9a99ed1ce2b"
  },
  "service": {
    "github": "https://github.com/vanallenlab/moalmanac-db",
    "name": "Molecular Oncology Almanac",
    "license": "GPL-2.0",
    "release": "draft",
    "url": "https://dev.moalmanac.org",
    "last_updated": "2026-04-09"
  },
  "data": [
    {
      "id": "ind:hpra.femara:0",
      "indication": "Adjuvant treatment of postmenopausal women with hormone receptor positive invasive early breast cancer.",
      "initial_approval_date": null,
      "initial_approval_url": null,
      "description": "The Republic of Ireland's Health Products Regulatory Authority (HPRA) has authorized letrozole for the adjuvant treatment of patients who are postmenopausal women with hormone receptor positive invasive early breast cancer.",
      "raw_biomarkers": null,
      "raw_cancer_type": "Breast cancer",
      "raw_therapeutics": "Letrozole",
      "icd10": null,
      "regimen_code": null,
      "reimbursement_category": null,
      "reimbursement_date": null,
      "reimbursement_details": null,
      "date_regular_approval": null,
      "date_accelerated_approval": null,
      "document": {
        "id": "doc:hpra.femara",
        "type": "Document",
        "documentType": "Regulatory approval",
        "name": "Femara (letrozole) [summary of product characteristics]. HPRA.",
        "title": null,
        "aliases": [],
        "description": "Novartis Ireland Limited. Femara 2.5 mg film-coated tablets (Letrozole) [summary of product characteristics]. Health Products Regulatory Authority website. https://assets.hpra.ie/products/Human/22619/Licence_PA0896-012-001_30082024144429.pdf. Revised August 2024. Accessed May 25, 2025.",
        "urls": [
          "https://www.hpra.ie/find-a-medicine/for-human-use/authorised-medicines/details/22619",
          "https://assets.hpra.ie/products/Human/22619/Licence_PA0896-012-001_30082024144429.pdf"
        ],
        "doi": null,
        "pmid": null,
        "extensions": [
          {
            "name": "agent",
            "value": {
              "id": "hpra",
              "type": "Agent",
              "agentType": "organization",
              "name": "Health Products Regulatory Authority",
              "description": "National register of authorized medicines in the Republic of Ireland.",
              "extensions": [
                {
                  "name": "last_updated",
                  "value": "2025-10-01",
                  "description": ""
                },
                {
                  "name": "url",
                  "value": "http://www.hpra.ie/homepage/medicines/medicines-information/find-a-medicine",
                  "description": ""
                }
              ]
            },
            "description": "The organization that published this document."
          },
          {
            "name": "company",
            "value": "Novartis Ireland Limited",
            "description": "The company that manufactures the cancer drug. Only applicable to market authorization documents."
          },
          {
            "name": "drug_name_brand",
            "value": "Femara",
            "description": "The brand name of the cancer drug, per this document. Only applicable to market authorization documents."
          },
          {
            "name": "drug_name_generic",
            "value": "letrozole",
            "description": "The generic name of the cancer drug, per this document. Only applicable to market authorization documents."
          },
          {
            "name": "first_publication_date",
            "value": null,
            "description": "The publication date for the initial version of this document."
          },
          {
            "name": "identification_number",
            "value": null,
            "description": "Identification number used by the publishing organization."
          },
          {
            "name": "publication_date",
            "value": "2024-08-30",
            "description": "The publication date for the document."
          },
          {
            "name": "status",
            "value": "Active",
            "description": "Whether this document is Active or Deprecated within moalmanac-db."
          }
        ]
      }
    }
  ]
}