{
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    "request_url": "https://api.moalmanac.org/indications?indication_id=ind%3Ahse%3A00400%3Aa",
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    "timestamp_received": "2026-11-09T16:14:08.358727Z",
    "timestamp_returned": "2026-11-09T16:14:08.360384Z",
    "trace_id": "2cbdd272-2d23-421e-8e57-5e6a045a2089"
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    "name": "Molecular Oncology Almanac",
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    "url": "https://moalmanac.org",
    "last_updated": "2026-10-08"
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  "data": [
    {
      "id": "ind:hse:00400:a",
      "type": "Indication",
      "description": "Treatment of chronic lymphocytic leukaemia (CLL) in the presence of 17p deletion or TP53 mutation in adult patients who are unsuitable for or have failed a B-cell receptor pathway inhibitor.",
      "contributions": [
        {
          "id": "ctrb:vanallenlab:2024-01-16:0",
          "type": "Contribution",
          "description": "Adding HSE approvals for reimbursement to database",
          "date": "2024-01-16",
          "contributor": {
            "id": "agent:user:vanallenlab",
            "type": "Agent",
            "agentType": "contributor",
            "name": "Van Allen lab",
            "description": "Van Allen lab, Dana-Farber Cancer Institute"
          }
        },
        {
          "id": "ctrb:hse:2018-12-01:0",
          "type": "Contribution",
          "description": "Indication approved for reimbursement.",
          "date": "2018-12-01",
          "contributor": {
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            "type": "Agent",
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            "name": "Health Service Executive",
            "description": "Regulatory agency that approves medicines for reimbursement by the public health system in the Republic of Ireland."
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      "reportedIn": [
        {
          "id": "doc:hse:00400",
          "type": "Document",
          "documentType": "Regulatory approval",
          "name": "Venetoclax Monotherapy. NCCP National SACT Regimen. HSE.",
          "title": null,
          "aliases": [],
          "description": "Venetoclax Monotherapy, 2021, version number 3, NCCP National SACT Regimen, NCCP, viewed 26/03/2026, https://healthservice.hse.ie/documents/6973/400_v3_Venetoclax_Monotherapy.pdf",
          "urls": [
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          "pmid": null,
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              "description": "The organization that published this document."
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              "description": "The company that manufactures the cancer drug. Only applicable to market authorization documents."
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              "description": "The brand name of the cancer drug, per this document. Only applicable to market authorization documents."
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              "description": "The publication date for the document."
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              "value": null,
              "description": "Identifier assigned by the regulatory agency, such as an FDA application number (e.g. NDA208716, BLA125427) or an EMA product number (e.g. EMEA/H/C/006184)."
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              "name": "status",
              "value": "Active",
              "description": "Whether this document is Active or Deprecated within moalmanac-db."
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          "value": "The Republic of Ireland's Health Service Executive (HSE) has approved venetoclax for reimbursement as a monotherapy treatment option for the treatment of patients with chronic lymphocytic leukemia (CLL) in the presence of 17p deletion or TP53 mutation in adult patients who are unsuitable for or have failed a B-cell receptor pathway inhibitor.",
          "description": "The description text for all Statements derived from this Indication."
        },
        {
          "name": "reimbursement_scheme",
          "value": "CDS",
          "description": "Current scheme used to reimburse indication."
        },
        {
          "name": "reimbursement_comment",
          "value": null,
          "description": "More details about the current reimbursement scheme(s)."
        }
      ]
    }
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}