{
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    "timestamp_received": "2026-11-09T16:14:04.537500Z",
    "timestamp_returned": "2026-11-09T16:14:04.539052Z",
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    "name": "Molecular Oncology Almanac",
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    "last_updated": "2026-10-08"
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  "data": [
    {
      "id": "ind:hse:00401:a",
      "type": "Indication",
      "description": "Treatment of adult patients with anaplastic lymphoma kinase (ALK)- positive advanced non-small cell lung cancer (NSCLC) previously treated with crizotinib.",
      "contributions": [
        {
          "id": "ctrb:vanallenlab:2024-01-16:0",
          "type": "Contribution",
          "description": "Adding HSE approvals for reimbursement to database",
          "date": "2024-01-16",
          "contributor": {
            "id": "agent:user:vanallenlab",
            "type": "Agent",
            "agentType": "contributor",
            "name": "Van Allen lab",
            "description": "Van Allen lab, Dana-Farber Cancer Institute"
          }
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        {
          "id": "ctrb:hse:2017-11-01:0",
          "type": "Contribution",
          "description": "Indication approved for reimbursement.",
          "date": "2017-11-01",
          "contributor": {
            "id": "agent:org:hse",
            "type": "Agent",
            "agentType": "organization",
            "name": "Health Service Executive",
            "description": "Regulatory agency that approves medicines for reimbursement by the public health system in the Republic of Ireland."
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      "reportedIn": [
        {
          "id": "doc:hse:00401",
          "type": "Document",
          "documentType": "Regulatory approval",
          "name": "Alectinib Monotherapy. NCCP National SACT Regimen. HSE.",
          "title": null,
          "aliases": [],
          "description": "Alectinib Monotherapy, 2025, version number 6, NCCP National SACT Regimen, NCCP, viewed 26/03/2026, https://healthservice.hse.ie/documents/6910/401_V6_Alectinib.pdf",
          "urls": [
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              "description": "The organization that published this document."
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            {
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              "value": "",
              "description": "The company that manufactures the cancer drug. Only applicable to market authorization documents."
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              "description": "The brand name of the cancer drug, per this document. Only applicable to market authorization documents."
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              "description": "The generic name of the cancer drug, per this document. Only applicable to market authorization documents."
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              "value": "2025-05-13",
              "description": "The publication date for the document."
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              "value": null,
              "description": "Identifier assigned by the regulatory agency, such as an FDA application number (e.g. NDA208716, BLA125427) or an EMA product number (e.g. EMEA/H/C/006184)."
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              "value": "Active",
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          "name": "status",
          "value": "Approved",
          "description": "Current approval status."
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          "value": "The Republic of Ireland's Health Service Executive (HSE) has approved alectinib for reimbursement as a treatment option for the treatment of adult patients with anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer (NSCLC) previously treated with crizotinib. This indication is specifically for patients whose tumors have been historically confirmed to be NSCLC with an ALK rearrangement identified by an approved and validated test method.",
          "description": "The description text for all Statements derived from this Indication."
        },
        {
          "name": "reimbursement_scheme",
          "value": "CDS",
          "description": "Current scheme used to reimburse indication."
        },
        {
          "name": "reimbursement_comment",
          "value": null,
          "description": "More details about the current reimbursement scheme(s)."
        }
      ]
    }
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}