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    "timestamp_received": "2026-04-25T12:44:20.615663+00:00Z",
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    "name": "Molecular Oncology Almanac",
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    "url": "https://dev.moalmanac.org",
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  "data": [
    {
      "id": "ind:hse.00525:b",
      "indication": "Treatment of women with hormone receptor (HR) positive, human epidermal growth factor receptor 2 (HER2) negative locally advanced or metastatic breast cancer in combination with an aromatase inhibitor or fulvestrant as initial endocrine based therapy or in women who have received prior endocrine therapy. In pre or perimenopausal women, the endocrine therapy should be combined with a luteinising hormone releasing hormone (LHRH) agonist.",
      "initial_approval_date": "2020-09-01",
      "initial_approval_url": null,
      "description": "The Republic of Ireland's Health Service Executive (HSE) has approved ribociclib in combination with an aromatase inhibitor or fulvestrant as an initial endocrine-based treatment option for the treatment of patients who are women with (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer or in women who have received prior endocrine therapy. In pre or perimenopausal women, the endocrine therapy should be combined with a luteinising hormone releasing hormone (LHRH) agonist.",
      "raw_biomarkers": null,
      "raw_cancer_type": "locally advanced or metastatic breast cancer",
      "raw_therapeutics": "Ribociclib in combination with an aromatase inhibitor",
      "icd10": null,
      "regimen_code": null,
      "reimbursement_category": null,
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      "date_accelerated_approval": null,
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        "name": "Ribociclib Therapy - 28 day. NCCP National SACT Regimen. HSE.",
        "title": null,
        "aliases": [],
        "description": "Ribociclib Therapy - 28 day, 2024, version number 5, NCCP National SACT Regimen, NCCP, viewed 26/03/2026, https://healthservice.hse.ie/documents/6629/525_v6_Ribociclib_Metastatic_hghzyyD.pdf",
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            "description": "The company that manufactures the cancer drug. Only applicable to market authorization documents."
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}