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    "timestamp_received": "2026-04-25T12:52:57.942507+00:00Z",
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    "name": "Molecular Oncology Almanac",
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    "url": "https://dev.moalmanac.org",
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  "data": [
    {
      "id": "ind:hse.P00760:a",
      "indication": "For the treatment of paediatric patients with solid tumours that display a Neurotrophic Tyrosine Receptor Kinase (NTRK) gene fusion, (i) who have a disease that is locally advanced, metastatic or where surgical resection is likely to result in severe morbidity, and (ii) who have no satisfactory treatment options",
      "initial_approval_date": "2023-05-01",
      "initial_approval_url": null,
      "description": "The Republic of Ireland's Health Service Executive (HSE) has approved larotrectinib monotherapy for reimbursement for the treatment of pediatric patients with solid tumors that display a Neurotrophic Tyrosine Receptor Kinase (NTRK) gene fusion. This indication is for patients whose disease is locally advanced, metastatic, or where surgical resection is likely to result in severe morbidity, and who have no satisfactory treatment options.",
      "raw_biomarkers": null,
      "raw_cancer_type": "Any solid tumor",
      "raw_therapeutics": "Larotrectinib",
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      "regimen_code": null,
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      "reimbursement_date": null,
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      "date_accelerated_approval": null,
      "document": {
        "id": "doc:hse.P00760",
        "type": "Document",
        "documentType": "Regulatory approval",
        "name": "Larotrectinib Monotherapy - Paediatric. NCCP National SACT Regimen. HSE.",
        "title": null,
        "aliases": [],
        "description": "Larotrectinib Monotherapy - Paediatric, 2024, version number 3, NCCP National SACT Regimen, NCCP, viewed 26/03/2026, https://healthservice.hse.ie/documents/6810/P760_V3_Larotrectinib_Therapy_Paediatric.pdf",
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                  "description": ""
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            "description": "The company that manufactures the cancer drug. Only applicable to market authorization documents."
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