{
  "meta": {
    "data_length": 1,
    "message": "Proposition id 749 retrieved successfully",
    "request_url": "http://api.moalmanac.org/propositions?proposition_id=749",
    "status": "success",
    "status_code": 200,
    "timestamp_elapsed": 0.009543,
    "timestamp_received": "2026-04-23T20:28:13.365289+00:00Z",
    "timestamp_returned": "2026-04-23T20:28:13.374832+00:00Z",
    "trace_id": "9b60d27d-0784-4524-8eee-4e73d4091e31"
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    "name": "Molecular Oncology Almanac",
    "license": "GPL-2.0",
    "release": "draft",
    "url": "https://dev.moalmanac.org",
    "last_updated": "2026-04-09"
  },
  "data": [
    {
      "id": 749,
      "type": "VariantTherapeuticResponseProposition",
      "predicate": "predictSensitivityTo",
      "biomarkers": [
        {
          "id": 84,
          "name": "17p deletion",
          "genes": [],
          "type": "CategoricalVariant",
          "extensions": [
            {
              "name": "biomarker_type",
              "value": "Copy Number (arm level)"
            },
            {
              "name": "chromosome",
              "value": "17"
            },
            {
              "name": "direction",
              "value": "Deletion"
            },
            {
              "name": "arm",
              "value": "p"
            }
          ]
        }
      ],
      "subjectVariant": {},
      "conditionQualifier": {
        "id": 84,
        "conceptType": "Disease",
        "name": "Chronic Lymphocytic Leukemia",
        "primaryCoding": {
          "id": "ncit:C3163",
          "code": "C3163",
          "name": "Chronic Lymphocytic Leukemia",
          "system": "https://evsexplore.semantics.cancer.gov",
          "systemVersion": "25.01d",
          "iris": [
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          ]
        },
        "mappings": [
          {
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            "coding": {
              "id": "oncotree:CLLSLL",
              "code": "CLLSLL",
              "name": "Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma",
              "system": "https://oncotree.mskcc.org",
              "systemVersion": "oncotree_2021_11_02",
              "iris": [
                "https://oncotree.mskcc.org/?version=oncotree_2021_11_02&field=CODE&search=CLLSLL"
              ]
            }
          }
        ]
      },
      "objectTherapeutic": {
        "id": 115,
        "conceptType": "Drug",
        "name": "Ibrutinib",
        "primaryCoding": {
          "id": "ncit:C81934",
          "code": "C81934",
          "name": "Ibrutinib",
          "system": "https://evsexplore.semantics.cancer.gov",
          "systemVersion": "25.01d",
          "iris": [
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        },
        "mappings": [],
        "extensions": [
          {
            "name": "therapy_strategy",
            "value": [
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            ],
            "description": "Associated therapeutic strategy or mechanism of action of the therapy."
          },
          {
            "name": "therapy_type",
            "value": "Targeted therapy",
            "description": "Type of cancer treatment from cancer.gov: https://www.cancer.gov/about-cancer/treatment/types"
          }
        ]
      }
    }
  ]
}